9VSM

Crystal structure of cystathionine gamma-synthase from Lactobacillus plantarum complexed with the cystathionine-bound external aldimine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cysteine gamma synthase/O-succinylhomoserine (Thiol)-lyase	polymer	381	41566.7	4	UniProt (F9URD2) Pfam (PF01053)	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
2	E, F, G, H (A, B, C, D)	(2~{S})-4-[(2~{R})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]sulfanyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]butanoic acid	non-polymer		451.4	4	Chemie (E9U)
3	I, J, K, L (A, B, C, D)	water	water		18.0	1500	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 373 (UniProt: F9URD2)

PDB	External Database	Details
Ala 203	Lys 203	engineered mutation
Leu 374	-	expression tag
Glu 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	166266.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1805.6
All*	Total formula weight	168072.4

*Water molecules are not included.