9VRR

Crystal structure of human PTPN2 with inhibitor WS3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Tyrosine-protein phosphatase non-receptor type 2	polymer	301	34989.6	2	UniProt (P17706) Pfam (PF00102)	Homo sapiens (human)	T-cell protein-tyrosine phosphatase,TCPTP
2	C, D (B, A)	5-[2-fluoranyl-4-[1-(3-methylbutyl)azetidin-3-yl]-6-oxidanyl-phenyl]-1,1-bis(oxidanylidene)-1,2,5-thiadiazolidin-3-one	non-polymer		371.4	2	Chemie (A1ETL)
3	E, F (B, A)	water	water		18.0	212	Chemie (HOH)

Sequence modifications

B, A: 5 - 296 (UniProt: P17706)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Pro 1	-	expression tag
Trp 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69979.3
Non-Polymers*	Number of molecules	2
	Total formula weight	742.9
All*	Total formula weight	70722.1

*Water molecules are not included.