9VRQ
Crystal structure of FOXC2/NFAT1 complex bound to ARRE2 DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Forkhead box protein C2 | polymer | 103 | 12330.2 | 1 | UniProt (Q99958) | Homo sapiens (human) | Forkhead-related protein FKHL14,Mesenchyme fork head protein 1,MFH-1 protein,Transcription factor FKH-14 |
| 2 | B (C) | ARRE2-S | polymer | 21 | 6491.2 | 1 | Homo sapiens | ||
| 3 | C (D) | ARRE2-AS | polymer | 21 | 6389.2 | 1 | Homo sapiens | ||
| 4 | D (N) | Nuclear factor of activated T-cells, cytoplasmic 2 | polymer | 287 | 32514.0 | 1 | UniProt (Q13469) | Homo sapiens (human) | NF-ATc2,NFATc2,NFAT pre-existing subunit,NF-ATp,T-cell transcription factor NFAT1 |
| 5 | E, F, G, H (A, C, D, N) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 72 - 172 (UniProt: Q99958)
N: 392 - 678 (UniProt: Q13469)
| PDB | External Database | Details |
|---|---|---|
| Gly 70 | - | expression tag |
| Pro 71 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 394 | Leu 394 | conflict |
| Val 395 | Pro 395 | conflict |
| Val 501 | Ile 501 | conflict |
| Ala 562 | Thr 562 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57724.6 | |
| All* | Total formula weight | 57724.6 |
