9VQM

Cryo-EM structure of Elapor1WT in tetrameric form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Endosome/lysosome-associated apoptosis and autophagy regulator 1	polymer	990	108851.3	1	UniProt (A0A0A0MQC6) Pfam (PF23032) Pfam (PF23091) Pfam (PF23031) Pfam (PF23087) Pfam (PF23089) UniProt (by SIFTS) (A2AFS3)	Mus musculus (mice)
2	B, C, D (B, C, D)	Endosome/lysosome-associated apoptosis and autophagy regulator 1	polymer	1004	110543.5	3	UniProt (A0A0A0MQC6) Pfam (PF23089) Pfam (PF23032) Pfam (PF23091) Pfam (PF23031) Pfam (PF23087) UniProt (by SIFTS) (A2AFS3)	Mus musculus (mice)
3	E, F, G (E, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	H, I, J, M, N... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG)
5	K, L, P (A, B)	COPPER (II) ION	non-polymer		63.5	3	Chemie (CU)

Sequence modifications

A: 41 - 1013 (UniProt: A0A0A0MQC6)

PDB	External Database	Details
Asp 24	-	expression tag
Tyr 25	-	expression tag
Lys 26	-	expression tag
Asp 27	-	expression tag
Asp 28	-	expression tag
Asp 29	-	expression tag
Asp 30	-	expression tag
Lys 31	-	expression tag
Gly 32	-	expression tag
Ser 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
Ser 40	-	expression tag

B, C, D: 45 - 1013 (UniProt: A0A0A0MQC6)

PDB	External Database	Details
Met 10	-	initiating methionine
Lys 11	-	expression tag
Thr 12	-	expression tag
Ile 13	-	expression tag
Ile 14	-	expression tag
Ala 15	-	expression tag
Leu 16	-	expression tag
Ser 17	-	expression tag
Tyr 18	-	expression tag
Ile 19	-	expression tag
Phe 20	-	expression tag
Cys 21	-	expression tag
Leu 22	-	expression tag
Val 23	-	expression tag
Phe 24	-	expression tag
Ala 25	-	expression tag
Asp 26	-	expression tag
Tyr 27	-	expression tag
Lys 28	-	expression tag
Asp 29	-	expression tag
Asp 30	-	expression tag
Asp 31	-	expression tag
Asp 32	-	expression tag
Lys 33	-	expression tag
Gly 34	-	expression tag
Ser 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
Ser 42	-	expression tag
Gly 43	-	expression tag
Met 44	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	440481.9
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	15
	Total formula weight	2845.1
All*	Total formula weight	444600.2

*Water molecules are not included.