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9VOR

Cryo-EM Structure of Human GPR158 Bound to Nanobody Nb20

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Metabotropic glycine receptorpolymer78188251.62UniProt (Q5T848)
Pfam (PF22572)
Pfam (PF00003)
Homo sapiens (human)mGlyR,G-protein coupled receptor 158
2C, D
(C, E)
Nb20polymer15016722.52Lama glama
3E, F, G, H, I...
(A, B)
CHOLESTEROLnon-polymer386.720Chemie (CLR)
4P
(A)
1,2-dioleoyl-sn-glycero-3-phosphoethanolaminenon-polymer744.01Chemie (PEE)
5Z
(B)
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositolnon-polymer836.11Chemie (PIE)
Sequence modifications
A, B: 1 - 775 (UniProt: Q5T848)
PDBExternal DatabaseDetails
Leu 776-expression tag
Glu 777-expression tag
Val 778-expression tag
Leu 779-expression tag
Phe 780-expression tag
Gln 781-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight209948.2
Non-Polymers*Number of molecules22
Total formula weight9313.2
All*Total formula weight219261.4
*Water molecules are not included.

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PDB entries from 2026-02-25

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