9VOB
Co-crystal structure of MAP4K6 in complex with compound 22
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Misshapen-like kinase 1 | polymer | 304 | 34627.8 | 1 | UniProt (Q8N4C8) Pfam (PF00069) | Homo sapiens (human) | GCK family kinase MiNK,MAPK/ERK kinase kinase kinase 6,MEK kinase kinase 6,MEKKK 6,Misshapen/NIK-related kinase,Mitogen-activated protein kinase kinase kinase kinase 6 |
| 2 | B (C) | ~{N}-[6-[[5-bromanyl-2-[(2-methyl-3,4-dihydro-1~{H}-isoquinolin-7-yl)amino]pyrimidin-4-yl]amino]quinoxalin-5-yl]methanesulfonamide | non-polymer | 555.5 | 1 | Chemie (A1EUL) | |||
| 3 | C (C) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
C: 7 - 310 (UniProt: Q8N4C8)
| PDB | External Database | Details |
|---|---|---|
| Ala 187 | Thr 187 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34627.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 555.5 | |
| All* | Total formula weight | 35183.3 |
