9VO9

Co-crystal structure of MAP4K4 in complex with compound 16

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (C, A, B, D)	Mitogen-activated protein kinase kinase kinase kinase 4	polymer	304	34833.0	4	UniProt (O95819) Pfam (PF00069)	Homo sapiens (human)	HPK/GCK-like kinase HGK,MAPK/ERK kinase kinase kinase 4,MEK kinase kinase 4,MEKKK 4,Nck-interacting kinase
2	E, F, G, H (C, A, B, D)	~{N}-[6-[[5-bromanyl-2-[(2-methyl-3,4-dihydro-1~{H}-isoquinolin-7-yl)amino]pyrimidin-4-yl]amino]quinoxalin-5-yl]-~{N}-methyl-methanesulfonamide	non-polymer		569.5	4	Chemie (A1EUK)
3	I, J, K, L (C, A, B, D)	water	water		18.0	81	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	139332.2
Non-Polymers*	Number of molecules	4
	Total formula weight	2277.9
All*	Total formula weight	141610.1

*Water molecules are not included.