9VNP

The complexes of IFN-gamma and A01BM-03 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	Interferon gamma	polymer	192	22111.6	1	UniProt (P01579) Pfam (PF00714)	Homo sapiens (human)	IFN-gamma,Immune interferon
2	B (A)	Light chain	polymer	218	23378.7	1		Homo sapiens
3	C (C)	Heavy chain	polymer	223	24084.1	1		Homo sapiens
4	D, E, F (L, A, C)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

L: 1 - 143 (UniProt: P01579)

PDB	External Database	Details
Gln 137	Arg 160	variant
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
Ser 152	-	expression tag
Ala 153	-	expression tag
Trp 154	-	expression tag
Ser 155	-	expression tag
His 156	-	expression tag
Pro 157	-	expression tag
Gln 158	-	expression tag
Phe 159	-	expression tag
Glu 160	-	expression tag
Lys 161	-	expression tag
Gly 162	-	expression tag
Gly 163	-	expression tag
Gly 164	-	expression tag
Ser 165	-	expression tag
Gly 166	-	expression tag
Gly 167	-	expression tag
Gly 168	-	expression tag
Gly 169	-	expression tag
Ser 170	-	expression tag
Gly 171	-	expression tag
Gly 172	-	expression tag
Ser 173	-	expression tag
Ala 174	-	expression tag
Trp 175	-	expression tag
Ser 176	-	expression tag
His 177	-	expression tag
Pro 178	-	expression tag
Gln 179	-	expression tag
Phe 180	-	expression tag
Glu 181	-	expression tag
Lys 182	-	expression tag
Gly 183	-	expression tag
Ser 184	-	expression tag
Asp 185	-	expression tag
Tyr 186	-	expression tag
Lys 187	-	expression tag
Asp 188	-	expression tag
Asp 189	-	expression tag
Asp 190	-	expression tag
Asp 191	-	expression tag
Lys 192	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69574.5
All*	Total formula weight	69574.5

*Water molecules are not included.