9VMN
Cryo-EM structure of the a-KG-OXGR1-Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha isoforms short | polymer | 356 | 41244.8 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 51 | 5660.5 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 4 | D (R) | 2-oxoglutarate receptor 1 | polymer | 295 | 33758.1 | 1 | UniProt (Q96P68) | Homo sapiens (human) | Alpha-ketoglutarate receptor 1,G-protein coupled receptor 80,G-protein coupled receptor 99,P2Y purinoceptor 15,P2Y15,P2Y-like GPCR,P2Y-like nucleotide receptor |
| 5 | E (S) | scFv16 | polymer | 247 | 26277.3 | 1 | synthetic construct | ||
| 6 | F (R) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 144139.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 146.1 | |
| All* | Total formula weight | 144285.5 |
