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9VM9

Crystal structure of FGFR3 in complex with 10s

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Fibroblast growth factor receptor 3polymer29232936.14UniProt (P22607)
Pfam (PF07714)
Homo sapiens (human)FGFR-3
2E, G, I, L
(A, B, C, D)
~{N}-[1-methyl-3-[2-[[5-methyl-1-(2-morpholin-4-ylethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]indol-6-yl]propanamidenon-polymer488.64Chemie (A1ESW)
3F, H, J, M
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
PubChem (888)
4K
(D)
GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
5N, O, P, Q
(A, B, C, D)
waterwater18.055Chemie (HOH)
Sequence modifications
A, B, C, D: 455 - 756 (UniProt: P22607)
PDBExternal DatabaseDetails
Gly 453-expression tag
Pro 454-expression tag
Ser 584Pro 572conflict
Gly 585Pro 573conflict
-Gly 574deletion
-Leu 575deletion
-Asp 576deletion
-Tyr 577deletion
-Ser 578deletion
-Phe 579deletion
-Asp 580deletion
-Thr 581deletion
-Cys 582deletion
-Lys 583deletion
-Pro 584deletion
-Pro 585deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight131744.5
Non-Polymers*Number of molecules9
Total formula weight2143.7
All*Total formula weight133888.1
*Water molecules are not included.

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PDB entries from 2026-05-20

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