Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fibroblast growth factor receptor 3 | polymer | 292 | 32936.1 | 4 | UniProt (P22607) Pfam (PF07714) | Homo sapiens (human) | FGFR-3 |
| 2 | E, G, I, L (A, B, C, D) | ~{N}-[1-methyl-3-[2-[[5-methyl-1-(2-morpholin-4-ylethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]indol-6-yl]propanamide | non-polymer | 488.6 | 4 | Chemie (A1ESW) | |||
| 3 | F, H, J, M (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | K (D) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 455 - 756 (UniProt: P22607)
| PDB | External Database | Details |
|---|---|---|
| Gly 453 | - | expression tag |
| Pro 454 | - | expression tag |
| Ser 584 | Pro 572 | conflict |
| Gly 585 | Pro 573 | conflict |
| - | Gly 574 | deletion |
| - | Leu 575 | deletion |
| - | Asp 576 | deletion |
| - | Tyr 577 | deletion |
| - | Ser 578 | deletion |
| - | Phe 579 | deletion |
| - | Asp 580 | deletion |
| - | Thr 581 | deletion |
| - | Cys 582 | deletion |
| - | Lys 583 | deletion |
| - | Pro 584 | deletion |
| - | Pro 585 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131744.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2143.7 | |
| All* | Total formula weight | 133888.1 |






