9VM7

Structure of DOCK6 tetramer complexed with Rac1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Dedicator of cytokinesis protein 6	polymer	2053	230265.3	4	UniProt (Q96HP0)	Homo sapiens (human)
2	B, D, F, H (B, D, F, H)	Ras-related C3 botulinum toxin substrate 1	polymer	184	20244.3	4	UniProt (P63000)	Homo sapiens (human)	Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1

Sequence modifications

A, C, E, G: 1 - 2047 (UniProt: Q96HP0)

PDB	External Database	Details
Gly -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D, F, H: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Ala 15	Gly 15	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	1002038.3
All*	Total formula weight	1002038.3

*Water molecules are not included.