9VLM
The X-RAY co-crystal structure of human FGFR2 and covalent inhibitor 10a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 2 | polymer | 303 | 34747.1 | 2 | UniProt (P21802) Pfam (PF07714) | Homo sapiens (human) | FGFR-2,K-sam,KGFR,Keratinocyte growth factor receptor |
| 2 | C, E (A, B) | ~{N}-[3-[2-[[3-[2-(dimethylamino)ethylsulfamoylmethyl]phenyl]amino]pyrimidin-4-yl]-1-methyl-indol-6-yl]propanamide | non-polymer | 535.7 | 2 | Chemie (A1ESP) | |||
| 3 | D, F (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A, B: 465 - 765 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Gly 463 | - | expression tag |
| Pro 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69494.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1255.5 | |
| All* | Total formula weight | 70749.7 |
