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9VJ4

Structure of a membrane-bound inositol phosphorylceramide synthase and ceramide complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Inositol phosphorylceramide synthase catalytic subunit AUR1polymer40145223.01UniProt (P36107)Saccharomyces cerevisiae S288CIPC synthase catalytic subunit AUR1,Aureobasidin A resistance protein,Phosphatidylinositol:ceramide phosphoinositol transferase
2B
(B)
Inositol phosphorylceramide synthase regulatory subunit KEI1polymer22125505.81UniProt (Q06346)Saccharomyces cerevisiae S288CICP synthase regulatory subunit KEI1,KEX2-cleavable protein essential for inositol phosphorylceramide synthesis
3C
(A)
~{N}-[(~{Z},2~{S},3~{R})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamidenon-polymer467.81Chemie (UJO)
4D, F
(A, B)
TETRADECANEnon-polymer198.42Chemie (C14)
5E
(A)
(2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoatenon-polymer635.91Chemie (46E)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70728.8
Non-Polymers*Number of molecules4
Total formula weight1500.4
All*Total formula weight72229.2
*Water molecules are not included.

250359

PDB entries from 2026-03-11

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