9VIZ

Cryo-EM structure of palytoxin-bound Na+,K+-ATPase in the transient state of dephosphorylation (E2~P)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	Na, K-ATPase alpha subunit	polymer	1028	113309.9	2	UniProt (Q4H132)	Squalus acanthias (spiny dogfish)
2	B, E (B, D)	Na+,K+-ATPase beta subunit	polymer	305	35176.1	2	UniProt (C4IX13)	Squalus acanthias (spiny dogfish)	Sodium/potassium-transporting ATPase subunit beta-1
3	C, F (G, E)	FXYD domain-containing ion transport regulator	polymer	94	10195.8	2	UniProt (Q70Q12)	Squalus acanthias (spiny dogfish)
4	G, K (F, K)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	2	In PDB GlyTouCan (G82348BZ)
5	H, L (H, L)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1114.0	2	In PDB GlyTouCan (G61751GZ)
6	I, M (I, M)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	2	In PDB GlyTouCan (G42466VF)
7	J, N (J, N)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
8	BA, CA, DA, IA, O... (B, G, C, A, D...)	CHOLESTEROL	non-polymer		386.7	8	Chemie (CLR)
9	AB, BB, EA, FA, GA... (E, G, C, A)	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		787.1	22	Chemie (PCW)
10	QA, W (C, A)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
11	RA, X (C, A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
12	SA, TA, Y, Z (C, A)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
13	AA, UA (A, C)	palytoxin	non-polymer		2680.1	2	Chemie (A1MA6)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	317363.7
Branched	Number of molecules	8
	Total formula weight	6980.4
Non-Polymers*	Number of molecules	40
	Total formula weight	26116.7
All*	Total formula weight	350460.8

*Water molecules are not included.