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9VG3

SIRT2 structure in complex with H3K18myr peptide: pre NAD binding state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-2polymer30033961.21UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (human)NAD-dependent protein defatty-acylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2-like protein 2
2B
(C)
Histone H3.1polymer6713.91UniProt (P68431)Homo sapiensHistone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
3C, D
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5F
(C)
MYRISTIC ACIDnon-polymer228.41Chemie (MYR)
6G, H
(A, C)
waterwater18.054Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34675.1
Non-Polymers*Number of molecules4
Total formula weight417.9
All*Total formula weight35093.0
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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