9VEQ
Crystal structure of Keap1 in complex with a small molecule inhibitor, KMN003
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kelch-like ECH-associated protein 1 | polymer | 290 | 31652.3 | 2 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (house mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | C, E (A, B) | 4-[1,4-bis[(4-ethoxyphenyl)sulfonylamino]naphthalen-2-yl]butanoic acid | non-polymer | 612.7 | 2 | Chemie (A1L98) | |||
| 3 | D, F (A, B) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B: 321 - 609 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Gly 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63304.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1317.5 | |
| All* | Total formula weight | 64622.1 |
