9VE2
Crystal Structure of Human Peroxiredoxin I in Complex with Fluvastatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxiredoxin-1 | polymer | 175 | 19337.1 | 2 | UniProt (Q06830) Pfam (PF00578) Pfam (PF10417) | Homo sapiens (human) | Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,Thioredoxin-dependent peroxiredoxin 1 |
| 2 | C (B) | (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | non-polymer | 411.5 | 1 | Chemie (115) PubChem (446155) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 484 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 175 (UniProt: Q06830)
| PDB | External Database | Details |
|---|---|---|
| Ser 52 | Cys 52 | engineered mutation |
| Ser 83 | Cys 83 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38674.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 411.5 | |
| All* | Total formula weight | 39085.6 |
