9VDI
Crystal structure of the recombinant A1-antitrypsin F51L/M351V/M358V triple mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-1-antitrypsin | polymer | 372 | 41816.7 | 2 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
Sequence modifications
A, B: 23 - 394 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Leu 51 | Phe 75 | engineered mutation |
| Gly 70 | Ala 94 | conflict |
| His 101 | Arg 125 | conflict |
| Val 351 | Met 375 | engineered mutation |
| Val 358 | Met 382 | engineered mutation |
| Asp 376 | Glu 400 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83633.5 | |
| All* | Total formula weight | 83633.5 |
