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9VDF

The crystal structure of IDH1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isocitrate dehydrogenase [NADP] cytoplasmicpolymer41747049.62UniProt (O75874)
Pfam (PF00180)
Homo sapiens (human)IDH,IDH1,Cytosolic NADP-isocitrate dehydrogenase,IDPc,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase
2C
(A)
(1~{R},4~{S},6~{R})-6-oxidanyl-2-(phenylmethyl)-2-azabicyclo[2.2.2]octan-3-onenon-polymer231.31Chemie (A1ERX)
3D
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4E
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
5F, G
(A, B)
waterwater18.0793Chemie (HOH)
Sequence modifications
A, B: 1 - 414 (UniProt: O75874)
PDBExternal DatabaseDetails
Ser 415-expression tag
Leu 416-expression tag
Glu 417-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight94099.1
Non-Polymers*Number of molecules3
Total formula weight1072.8
All*Total formula weight95171.9
*Water molecules are not included.

256158

PDB entries from 2026-07-08

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