9VA1

Structure of the ACE2-B0AT1 bound with tryptophan

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, A)	Angiotensin-converting enzyme 2	polymer	808	93504.6	2	UniProt (Q9BYF1) Pfam (PF01401) Pfam (PF16959)	Homo sapiens (human)	Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15
2	B, D (D, B)	Sodium-dependent neutral amino acid transporter B(0)AT1	polymer	652	73087.1	2	UniProt (Q695T7) Pfam (PF00209)	Homo sapiens (human)	Solute carrier family 6 member 19,System B(0) neutral amino acid transporter AT1
3	E, F (D, B)	TRYPTOPHAN	non-polymer		204.2	2	Chemie (TRP)

Sequence modifications

C, A: 18 - 805 (UniProt: Q9BYF1)

PDB	External Database	Details
Trp 10	-	expression tag
Ser 11	-	expression tag
His 12	-	expression tag
Pro 13	-	expression tag
Gln 14	-	expression tag
Phe 15	-	expression tag
Glu 16	-	expression tag
Lys 17	-	expression tag
Leu 806	-	expression tag
Glu 807	-	expression tag
His 808	-	expression tag
His 809	-	expression tag
His 810	-	expression tag
His 811	-	expression tag
His 812	-	expression tag
His 813	-	expression tag
His 814	-	expression tag
His 815	-	expression tag
His 816	-	expression tag
His 817	-	expression tag

D, B: 2 - 634 (UniProt: Q695T7)

PDB	External Database	Details
Asp -17	-	expression tag
Tyr -16	-	expression tag
Lys -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Lys -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Pro -7	-	expression tag
Asp -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Asp -3	-	expression tag
Ala -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	333183.3
Non-Polymers*	Number of molecules	2
	Total formula weight	408.4
All*	Total formula weight	333591.8

*Water molecules are not included.