9V9H

Cryo-EM structure of the cPRC1-di-nucleosome (tight) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, K, M (A, E, K, M)	Histone H3.1	polymer	136	15437.2	4	UniProt (P68431)	Homo sapiens (human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F, Q, R (B, F, Q, R)	Histone H4	polymer	103	11394.4	4	UniProt (P62805)	Homo sapiens (human)
3	C, G, L, O (C, G, L, O)	Histone H2A type 1-H	polymer	128	13935.3	4	UniProt (Q96KK5)	Homo sapiens (human)	H2A-clustered histone 12,Histone H2A/s
4	D, H, N, P (D, H, N, P)	Histone H2B type 1-C/E/F/G/I	polymer	126	13937.2	4	UniProt (P62807)	Homo sapiens (human)	Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l
5	I (I)	DNA (276-MER)	polymer	276	85179.1	1		Homo sapiens
6	J (J)	DNA (276-MER)	polymer	276	85290.2	1		Homo sapiens
7	S, U (S, U)	Polycomb complex protein BMI-1	polymer	326	37006.1	2	UniProt (P35226)	Homo sapiens (human)	Polycomb group RING finger protein 4,RING finger protein 51
8	T, V (T, V)	E3 ubiquitin-protein ligase RING2	polymer	336	37706.4	2	UniProt (Q99496)	Homo sapiens (human)	Huntingtin-interacting protein 2-interacting protein 3,HIP2-interacting protein 3,Protein DinG,RING finger protein 1B,RING1b,RING finger protein 2,RING finger protein BAP-1,RING-type E3 ubiquitin transferase RING2
9	AA, BA, CA, DA, W... (U, V, S, T)	ZINC ION	non-polymer		65.4	8	Chemie (ZN) PubChem (32051)

Contents of the asymmetric unit

Polymers	Number of chains	22
	Total formula weight	538710.6
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	539233.8

*Water molecules are not included.