9V90
Crystal structure of the PDZ tandem of syntenin in complex with PDZ2 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Syntenin-1 | polymer | 163 | 17717.4 | 2 | UniProt (O00560) Pfam (PF00595) | Homo sapiens (human) | Melanoma differentiation-associated protein 9,MDA-9,Pro-TGF-alpha cytoplasmic domain-interacting protein 18,TACIP18,Scaffold protein Pbp1,Syndecan-binding protein 1 |
| 2 | C, F (A, B) | (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid | non-polymer | 304.3 | 2 | Chemie (LKV) PubChem (132352592) | |||
| 3 | D, E, G (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) PubChem (175) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35434.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 785.8 | |
| All* | Total formula weight | 36220.5 |
