9V6V
The complex structure of HnH6H and 6-hydroxyhyoscyamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hyoscyamine 6-dioxygenase | polymer | 386 | 43105.7 | 1 | UniProt (P24397) | Hyoscyamus niger (henbane) | Hyoscyamine 6-beta-hydroxylase |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) PubChem (27284) | |||
| 3 | C (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) PubChem (51) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | F (A) | (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate | non-polymer | 305.4 | 1 | Chemie (OVR) PubChem (6918612) | |||
| 7 | G (A) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A: 1 - 344 (UniProt: P24397)
| PDB | External Database | Details |
|---|---|---|
| Ile 115 | Val 115 | conflict |
| Gly 345 | - | expression tag |
| Gly 346 | - | expression tag |
| Lys 347 | - | expression tag |
| Gly 348 | - | expression tag |
| Pro 349 | - | expression tag |
| Gly 350 | - | expression tag |
| Asp 351 | - | expression tag |
| Gly 352 | - | expression tag |
| Pro 353 | - | expression tag |
| Gly 354 | - | expression tag |
| Gly 355 | - | expression tag |
| Ser 356 | - | expression tag |
| Gly 357 | - | expression tag |
| Gly 358 | - | expression tag |
| Pro 359 | - | expression tag |
| Arg 360 | - | expression tag |
| Gly 361 | - | expression tag |
| Gly 362 | - | expression tag |
| Glu 363 | - | expression tag |
| Asn 364 | - | expression tag |
| Leu 365 | - | expression tag |
| Tyr 366 | - | expression tag |
| Phe 367 | - | expression tag |
| Gln 368 | - | expression tag |
| Ser 369 | - | expression tag |
| Gly 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| Gly 379 | - | expression tag |
| Gly 380 | - | expression tag |
| Arg 381 | - | expression tag |
| Gly 382 | - | expression tag |
| Gly 383 | - | expression tag |
| Ala 384 | - | expression tag |
| Ala 385 | - | expression tag |
| Ala 386 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43105.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 634.9 | |
| All* | Total formula weight | 43740.5 |
