9V6S
Cryo-EM structure of a single cPRC1 complex engaged on one face of an endogenous 147-bp mononucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B, E (G, C) | Histone H2A type 1-H | polymer | 128 | 13935.3 | 2 | UniProt (Q96KK5) | Homo sapiens (human) | H2A-clustered histone 12,Histone H2A/s |
| 3 | D, F (D, H) | Histone H2B type 1-C/E/F/G/I | polymer | 126 | 13937.2 | 2 | UniProt (P62807) | Homo sapiens (human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
| 4 | G, H (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) | Homo sapiens (human) | |
| 5 | I (I) | DNA (144-MER) | polymer | 144 | 44217.2 | 1 | Homo sapiens | ||
| 6 | J (J) | DNA (145-MER) | polymer | 145 | 44992.6 | 1 | Homo sapiens | ||
| 7 | K (M) | Polycomb complex protein BMI-1 | polymer | 326 | 37006.1 | 1 | UniProt (P35226) | Homo sapiens (human) | Polycomb group RING finger protein 4,RING finger protein 51 |
| 8 | L (N) | E3 ubiquitin-protein ligase RING2 | polymer | 336 | 37706.4 | 1 | UniProt (Q99496) | Homo sapiens (human) | Huntingtin-interacting protein 2-interacting protein 3,HIP2-interacting protein 3,Protein DinG,RING finger protein 1B,RING1b,RING finger protein 2,RING finger protein BAP-1,RING-type E3 ubiquitin transferase RING2 |
| 9 | M, N, O, P (M, N) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 273330.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 273592.1 |
