9V5P
Human DNMT1 (aa 698-1616) in complex with hemimethylated dsDNA and inhibitor DMT207
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 919 | 103882.1 | 1 | UniProt (P26358) Pfam (PF01426) Pfam (PF00145) | Homo sapiens (human) | Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,DNA MTase HsaI,M.HsaI,MCMT |
| 2 | B (E) | DNA (5'-D(*CP*CP*TP*TP*CP*CP*GP*TP*AP*AP*GP*T)-3') | polymer | 12 | 3613.4 | 1 | Homo sapiens | ||
| 3 | C (B) | DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3') | polymer | 12 | 3725.5 | 1 | Homo sapiens | ||
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 5 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (439155) | |||
| 6 | G (E) | (2~{R})-2-[3,5-dicyano-1-[2-[2-(dimethylamino)ethyl-methyl-amino]-2-oxidanylidene-ethyl]-4-ethyl-pyrrolo[2,3-b]pyridin-6-yl]sulfanyl-2-(4-methoxyphenyl)ethanamide | non-polymer | 533.6 | 1 | Chemie (A1EQ2) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 111221.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1048.9 | |
| All* | Total formula weight | 112269.9 |
