9V4O

Cryo-EM structure of A. thaliana MET1 with bound SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA (cytosine-5)-methyltransferase 1	polymer	1574	177588.1	1	UniProt (P34881) Pfam (PF12047) Pfam (PF01426) Pfam (PF00145)	Arabidopsis thaliana (thale cress)	DNA methyltransferase 01,DNA methyltransferase 2,DNA methyltransferase AthI,DNA Metase AthI,M.AthI,DNA methyltransferase DDM2,Protein DECREASED DNA METHYLATION 2
2	B (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 1 - 1534 (UniProt: P34881)

PDB	External Database	Details
Met -39	-	initiating methionine
Ser -38	-	expression tag
Tyr -37	-	expression tag
Tyr -36	-	expression tag
His -35	-	expression tag
His -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Asp -25	-	expression tag
Tyr -24	-	expression tag
Asp -23	-	expression tag
Ile -22	-	expression tag
Asp -21	-	expression tag
Tyr -20	-	expression tag
Lys -19	-	expression tag
Asp -18	-	expression tag
Asp -17	-	expression tag
Asp -16	-	expression tag
Asp -15	-	expression tag
Lys -14	-	expression tag
Pro -13	-	expression tag
Thr -12	-	expression tag
Thr -11	-	expression tag
Glu -10	-	expression tag
Asn -9	-	expression tag
Leu -8	-	expression tag
Tyr -7	-	expression tag
Phe -6	-	expression tag
Gln -5	-	expression tag
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	177588.1
Non-Polymers*	Number of molecules	2
	Total formula weight	449.8
All*	Total formula weight	178037.9

*Water molecules are not included.