9V4E
Crystal Structure of Gallus gallus c-Src Kinase Domain with Point mutation Y416D and Deletion of Residues N414, T417, and R419 Bound to AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 282 | 32198.0 | 1 | UniProt (P00523) | Gallus gallus (chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A: 22 - 301 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Ser 20 | - | expression tag |
| Met 21 | - | expression tag |
| - | Asn 414 | deletion |
| Asp 186 | Tyr 416 | engineered mutation |
| - | Thr 417 | deletion |
| - | Arg 419 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32198.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 32728.5 |
