9V3E

A broad-spectrum neutralizing antibody targeting the F protein of NiV and HeV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, B, C)	Fusion glycoprotein F0	polymer	502	55495.4	3	UniProt (Q9IH63)	Nipah virus	Protein F
2	B, D, F (E, F, G)	C-type nanoantibody	polymer	131	15008.8	3		Homo sapiens
3	G, H, I, J, K... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG)

Sequence modifications

A, B, C: 27 - 487 (UniProt: Q9IH63)

PDB	External Database	Details
Cys 104	Leu 104	conflict
Cys 114	Ile 114	conflict
Phe 172	Leu 172	conflict
Pro 191	Ser 191	conflict
Met 488	-	expression tag
Lys 489	-	expression tag
Gln 490	-	expression tag
Ile 491	-	expression tag
Glu 492	-	expression tag
Asp 493	-	expression tag
Lys 494	-	expression tag
Ile 495	-	expression tag
Glu 496	-	expression tag
Glu 497	-	expression tag
Ile 498	-	expression tag
Leu 499	-	expression tag
Ser 500	-	expression tag
Lys 501	-	expression tag
Ile 502	-	expression tag
Tyr 503	-	expression tag
His 504	-	expression tag
Ile 505	-	expression tag
Glu 506	-	expression tag
Asn 507	-	expression tag
Glu 508	-	expression tag
Ile 509	-	expression tag
Ala 510	-	expression tag
Arg 511	-	expression tag
Ile 512	-	expression tag
Lys 513	-	expression tag
Lys 514	-	expression tag
Leu 515	-	expression tag
Ile 516	-	expression tag
Gly 517	-	expression tag
Glu 518	-	expression tag
Gly 519	-	expression tag
Ser 520	-	expression tag
Gly 521	-	expression tag
Gly 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag
His 527	-	expression tag
His 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	211512.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2654.5
All*	Total formula weight	214167.2

*Water molecules are not included.