9V0H

Crystal structure of human SIRT5 in complex with inhibitor 0904

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NAD-dependent protein deacylase sirtuin-5, mitochondrial	polymer	269	29282.4	2	UniProt (Q9NXA8) Pfam (PF02146)	Homo sapiens (human)	Regulatory protein SIR2 homolog 5,SIR2-like protein 5
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
3	D, F (A, B)	3-[[(~{E})-1-[3-[[2-(6-ethoxypyridin-3-yl)-5-[[(1~{R})-1-phenylpropyl]carbamoyl]pyrimidin-4-yl]amino]propylamino]-2-nitro-ethenyl]amino]propanoic acid	non-polymer		592.6	2	Chemie (A1EQQ)
4	G, H (A, B)	water	water		18.0	762	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58564.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.1
All*	Total formula weight	59880.9

*Water molecules are not included.