9UZL
EMCV IRES captured on mammalian 40S ribosome with initiator tRNA and eIF2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (2) | 18S ribosomal RNA | polymer | 1863 | 600900.6 | 1 | GenBank (283837872) | Oryctolagus cuniculus (rabbit) | |
| 2 | B (A) | Eukaryotic translation initiation factor 2 subunit 1 | polymer | 315 | 36157.2 | 1 | Oryctolagus cuniculus | ||
| 3 | C (B) | Eukaryotic translation initiation factor 2 subunit 3 | polymer | 485 | 52500.0 | 1 | Oryctolagus cuniculus | ||
| 4 | D (C) | Small ribosomal subunit protein uS2 | polymer | 295 | 32928.0 | 1 | UniProt (G1TLT8) | Oryctolagus cuniculus (rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
| 5 | E (D) | Small ribosomal subunit protein eS1 | polymer | 264 | 29929.0 | 1 | UniProt (G1TN72) | Oryctolagus cuniculus (rabbit) | |
| 6 | F (E) | Small ribosomal subunit protein uS5 | polymer | 226 | 24814.3 | 1 | Oryctolagus cuniculus | ||
| 7 | G (F) | Small ribosomal subunit protein uS3 | polymer | 243 | 26715.3 | 1 | UniProt (G1TNM3) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S3 |
| 8 | H (G) | Small ribosomal subunit protein eS4 | polymer | 263 | 29658.9 | 1 | UniProt (G1TK17) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S4 |
| 9 | I (H) | Small ribosomal subunit protein uS7 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S5 |
| 10 | J (I) | Small ribosomal subunit protein eS6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S6 |
| 11 | K (J) | Small ribosomal subunit protein eS7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S7 |
| 12 | L (K) | Small ribosomal subunit protein eS8 | polymer | 206 | 23902.9 | 1 | UniProt (G1TJW1) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S8 |
| 13 | M (L) | Small ribosomal subunit protein uS4 | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S9 |
| 14 | N (M) | Small ribosomal subunit protein eS10 | polymer | 225 | 24854.5 | 1 | UniProt (A0AAG1W9A6) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S10 |
| 15 | O (N) | Small ribosomal subunit protein uS17 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S11 |
| 16 | P (O) | Small ribosomal subunit protein eS12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S12 |
| 17 | Q (P) | Small ribosomal subunit protein uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S13 |
| 18 | R (Q) | Ribosomal protein S14 | polymer | 168 | 18134.0 | 1 | UniProt (A0AAA9WYR1) | Oryctolagus cuniculus (rabbit) | |
| 19 | S (R) | Small ribosomal subunit protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S15 |
| 20 | T (S) | Small ribosomal subunit protein uS9 | polymer | 146 | 16477.4 | 1 | UniProt (G1SGX4) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S16 |
| 21 | U (T) | Small ribosomal subunit protein eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S17 |
| 22 | V (U) | Small ribosomal subunit protein uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S18 |
| 23 | W (V) | Small ribosomal subunit protein eS19 | polymer | 141 | 15812.3 | 1 | UniProt (G1TN62) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S19 |
| 24 | X (W) | Small ribosomal subunit protein uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S20 |
| 25 | Y (X) | Small ribosomal subunit protein eS21 | polymer | 82 | 8896.1 | 1 | UniProt (G1TM82) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S21 |
| 26 | Z (Y) | Small ribosomal subunit protein uS8 | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S15a |
| 27 | AA (Z) | Small ribosomal subunit protein uS12 | polymer | 143 | 15844.7 | 1 | UniProt (G1SZ47) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S23 |
| 28 | BA (a) | 40S ribosomal protein S24 | polymer | 126 | 14575.2 | 1 | UniProt (G1TS40) | Oryctolagus cuniculus (rabbit) | |
| 29 | CA (b) | Small ribosomal subunit protein eS26 | polymer | 115 | 12961.5 | 1 | UniProt (G1TFE8) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S26 |
| 30 | DA (c) | Small ribosomal subunit protein eS27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S27 |
| 31 | EA (d) | Small ribosomal subunit protein eS28 | polymer | 64 | 7263.4 | 1 | UniProt (G1TIB4) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S28 |
| 32 | FA (e) | Small ribosomal subunit protein uS14 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S29 |
| 33 | GA (f) | Ubiquitin-ribosomal protein eS31 fusion protein | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) | Oryctolagus cuniculus (rabbit) | |
| 34 | HA (g) | Small ribosomal subunit protein RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) | Oryctolagus cuniculus (rabbit) | Receptor of activated protein C kinase 1 |
| 35 | IA (h) | Small ribosomal subunit protein eS25 | polymer | 125 | 13776.2 | 1 | Oryctolagus cuniculus | ||
| 36 | JA (i) | Small ribosomal subunit protein eS30 | polymer | 59 | 6741.0 | 1 | UniProt (G1T8A2) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S30 |
| 37 | KA (l) | Small ribosomal subunit protein eS32 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L41,Large ribosomal subunit protein eL41 |
| 38 | LA (y) | Initiator tRNA | polymer | 75 | 24231.5 | 1 | Oryctolagus cuniculus | ||
| 39 | MA (z) | Encephalomyocarditis viral IRES | polymer | 93 | 29887.9 | 1 | GenBank (485965777) | Encephalomyocarditis virus |
Sequence modifications
M: -59 - 165 (UniProt: A0AAG1W9A6)
X: 1 - 82 (UniProt: G1TM82)
z: 517 - 601 (GenBank: 485965777)
| PDB | External Database | Details |
|---|---|---|
| Thr -30 | Ala 30 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Asn 3 | conflict |
| Asn 4 | Asp 4 | conflict |
| Pro 33 | Gln 33 | conflict |
| Ser 50 | Phe 50 | conflict |
| His 76 | Asp 76 | conflict |
| PDB | External Database | Details |
|---|---|---|
| A 831 | - | expression tag |
| A 832 | - | expression tag |
| U 833 | - | expression tag |
| A 834 | - | expression tag |
| U 835 | - | expression tag |
| G 836 | - | expression tag |
| G 837 | - | expression tag |
| C 838 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 39 |
| Total formula weight | 1365094.3 | |
| All* | Total formula weight | 1365094.3 |
