9UY1

Crystal structure of UMPK from S. aureus in complex with ATP and GTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (C, A, B, D, E...)	Uridylate kinase	polymer	248	27193.5	18	UniProt (Q2FZ22) Pfam (PF00696)	Staphylococcus aureus subsp. aureus NCTC 8325	UK,Uridine monophosphate kinase,UMP kinase,UMPK
2	BA, CA, DA, EA, FA... (I, J, K, L, M...)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	12	Chemie (GTP)
3	LA, MA, NA, T (R, C)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL) PubChem (753)
4	KA, U (R, A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
5	AA, GA, V, W (H, N, B, D)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
6	AB, BB, CB, DB, EB... (N, O, P, Q, R...)	water	water		18.0	51	Chemie (HOH)

Sequence modifications

C, A, B, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 240 (UniProt: Q2FZ22)

PDB	External Database	Details
Met -7	-	initiating methionine
Gly -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	489482.7
Non-Polymers*	Number of molecules	22
	Total formula weight	9529.7
All*	Total formula weight	499012.4

*Water molecules are not included.