9UXV

Crystal structure of GSDME

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Gasdermin-E, N-terminal,Gasdermin-D, N-terminal,Gasdermin-D, p40,Deafness, autosomal dominant 5	polymer	474	51882.4	2	UniProt (O60443) UniProt (Q9D8T2) UniProt (Q6J2R6) Pfam (PF04598) Pfam (PF17708)	Homo sapiens (human)	GSDME-NT,GSDMD-NT,mGSDMD-NTD,p30,Dfna5,Gasdermin Eb

Sequence modifications

A, B: 1 - 245 (UniProt: O60443)

PDB	External Database	Details
Ser -5	-	expression tag
Gly -4	-	expression tag
Pro -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag
Thr 142	Pro 142	conflict

A, B: 246 - 254 (UniProt: Q9D8T2)
A, B: 255 - 264 (UniProt: Q9D8T2)
A, B: 265 - 472 (UniProt: Q6J2R6)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103764.8
All*	Total formula weight	103764.8

*Water molecules are not included.