9UWI
Cryo-EM structure of human V1aR bound with atosiban at a resolution of 2.8 angstrom
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Vasopressin V1a receptor | polymer | 386 | 43695.1 | 2 | UniProt (P37288) | Homo sapiens (human) | V1aR,AVPR V1a,Antidiuretic hormone receptor 1a,Vascular/hepatic-type arginine vasopressin receptor |
| 2 | C, D (C, D) | Atosiban | polymer | 10 | 995.2 | 2 | synthetic construct | ||
| 3 | E, F, G, H (A, B) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) |
Sequence modifications
A, B: 33 - 418 (UniProt: P37288)
| PDB | External Database | Details |
|---|---|---|
| Cys 341 | Ser 341 | engineered mutation |
| Lys 344 | Asn 344 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89380.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1546.6 | |
| All* | Total formula weight | 90927.2 |
