9UW4

The complex of human pMEK1 and uERK1 (ANP)(from pY204ERK1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Mitogen-activated protein kinase 3	polymer	388	44399.8	1	UniProt (P27361)	Homo sapiens (human)	MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,p44-ERK1
2	B (A)	Dual specificity mitogen-activated protein kinase kinase 1	polymer	403	45001.3	1	UniProt (Q02750)	Homo sapiens (human)	MAP kinase kinase 1,MAPKK 1,MKK1,ERK activator kinase 1,MAPK/ERK kinase 1,MEK 1
3	C (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
4	D, E (B, A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)

Sequence modifications

B: 1 - 379 (UniProt: P27361)

PDB	External Database	Details
His 0	-	expression tag
Leu 380	-	expression tag
Glu 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag

A: 1 - 393 (UniProt: Q02750)

PDB	External Database	Details
Leu 394	-	expression tag
Glu 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89401.1
Non-Polymers*	Number of molecules	3
	Total formula weight	1036.7
All*	Total formula weight	90437.8

*Water molecules are not included.