9UVQ

Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2H4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Oxytocin receptor	polymer	343	37981.4	1	UniProt (P30559) Pfam (PF00001)	Homo sapiens (human)	OT-R
2	B (B)	Nanobody Nb2H4	polymer	30	3751.2	1		Vicugna pacos

Sequence modifications

A: 35 - 334 (UniProt: P30559)

PDB	External Database	Details
His 65	Arg 65	conflict
Ala 153	Asp 153	conflict
Lys 325	Asn 325	conflict
Met 333	Thr 333	conflict
Ala 1001	-	expression tag
Phe 1002	-	expression tag
Lys 1003	-	expression tag
Ile 1004	-	expression tag
Trp 1005	-	expression tag
Gln 1006	-	expression tag
Asn 1007	-	expression tag
Ser 1008	-	expression tag
Ala 1009	-	expression tag
Leu 1010	-	expression tag
Gly 1011	-	expression tag
Lys 1012	-	expression tag
Glu 1013	-	expression tag
Leu 1014	-	expression tag
Ala 1015	-	expression tag
Ala 1016	-	expression tag
Glu 1085	-	expression tag
Pro 1086	-	expression tag
Val 1087	-	expression tag
Ala 1088	-	expression tag
Ile 1089	-	expression tag
Leu 1090	-	expression tag
Thr 1091	-	expression tag
Leu 1092	-	expression tag
Ser 1093	-	expression tag
Phe 1094	-	expression tag
Lys 1095	-	expression tag
Ala 1119	-	expression tag
Tyr 1120	-	expression tag
Lys 1121	-	expression tag
Gly 1122	-	expression tag
Leu 1123	-	expression tag
Glu 1124	-	expression tag
Glu 1125	-	expression tag
Gly 1126	-	expression tag
Ser 1127	-	expression tag
Lys 1128	-	expression tag
Ala 1129	-	expression tag
Gly 1130	-	expression tag
Glu 1131	-	expression tag
Ala 1132	-	expression tag
Thr 1133	-	expression tag
Met 1134	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41732.6
All*	Total formula weight	41732.6

*Water molecules are not included.