9UV8
Crystal structure of HLA-A*11:01 in complex with KRAS G12D 9-mer peptide (VVGADGVGK)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 276 | 31986.3 | 1 | UniProt (P04439) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I antigen,Human leukocyte antigen A,HLA-A |
| 2 | B (B) | Beta-2-microglobulin | polymer | 122 | 14165.8 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | KRAS G12D-9mer (VVGADGVGK) | polymer | 9 | 801.9 | 1 | Homo sapiens | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 1 - 275 (UniProt: P04439)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Tyr 9 | Phe 33 | variant |
| Asp 90 | Ala 114 | variant |
| Pro 105 | Ser 129 | variant |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 100 | - | expression tag |
| Ser 101 | - | expression tag |
| Gly 102 | - | expression tag |
| Gly 103 | - | expression tag |
| Ser 104 | - | expression tag |
| Gly 105 | - | expression tag |
| Ala 106 | - | expression tag |
| Gly 107 | - | expression tag |
| Leu 108 | - | expression tag |
| Asn 109 | - | expression tag |
| Asp 110 | - | expression tag |
| Ile 111 | - | expression tag |
| Phe 112 | - | expression tag |
| Glu 113 | - | expression tag |
| Ala 114 | - | expression tag |
| Gln 115 | - | expression tag |
| Lys 116 | - | expression tag |
| Ile 117 | - | expression tag |
| Glu 118 | - | expression tag |
| Trp 119 | - | expression tag |
| His 120 | - | expression tag |
| Glu 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46953.9 | |
| All* | Total formula weight | 46953.9 |
