9UUK

Crystal structure of the mu2 subunit of the clathrin-adaptor protein 2 (AP2) bound to HPV16 E7(residues 22-32; S31E and S32E)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	AP-2 complex subunit mu	polymer	281	32124.7	1	UniProt (P84092) Pfam (PF00928)	Rattus norvegicus (Norway rat)	AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein
2	B (B)	Protein E7	polymer	11	1418.5	1	UniProt (P03129)	Human papillomavirus 16

Sequence modifications

A: 158 - 435 (UniProt: P84092)

PDB	External Database	Details
Gly 155	-	expression tag
His 156	-	expression tag
Met 157	-	expression tag

B: 22 - 32 (UniProt: P03129)

PDB	External Database	Details
Glu 31	Ser 31	engineered mutation
Glu 32	Ser 32	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33543.2
All*	Total formula weight	33543.2

*Water molecules are not included.