9UT7

The Primase module of the helicase-primase complex from HHV1 bound with ssDNA and pritelivir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Ubiquitin-like protein SMT3,DNA primase	polymer	1195	130399.0	1	UniProt (Q12306) UniProt (P10236)	Saccharomyces cerevisiae S288C
2	B (C)	Ubiquitin-like protein SMT3,DNA helicase/primase complex-associated protein	polymer	887	95846.4	1	UniProt (Q12306) UniProt (P10192)	Saccharomyces cerevisiae S288C	HEPA,Primase-associated factor

Sequence modifications

B: -95 - 0 (UniProt: Q12306)

PDB	External Database	Details
Met -136	-	initiating methionine
Ser -135	-	expression tag
Tyr -134	-	expression tag
Tyr -133	-	expression tag
His -132	-	expression tag
His -131	-	expression tag
His -130	-	expression tag
His -129	-	expression tag
His -128	-	expression tag
His -127	-	expression tag
Asp -126	-	expression tag
Tyr -125	-	expression tag
Asp -124	-	expression tag
Ile -123	-	expression tag
Pro -122	-	expression tag
Thr -121	-	expression tag
Thr -120	-	expression tag
Glu -119	-	expression tag
Asn -118	-	expression tag
Leu -117	-	expression tag
Tyr -116	-	expression tag
Phe -115	-	expression tag
Gln -114	-	expression tag
Gly -113	-	expression tag
Ile -112	-	expression tag
Thr -111	-	expression tag
Ser -110	-	expression tag
Leu -109	-	expression tag
Tyr -108	-	expression tag
Lys -107	-	expression tag
Lys -106	-	expression tag
Ala -105	-	expression tag
Gly -104	-	expression tag
Phe -103	-	expression tag
Leu -102	-	expression tag
Gln -101	-	expression tag
Leu -100	-	expression tag
Gly -99	-	expression tag
Ser -98	-	expression tag
Leu -97	-	expression tag
Gln -96	-	expression tag
Thr -34	Arg 64	engineered mutation
Glu -27	Arg 71	engineered mutation

B: 1 - 1058 (UniProt: P10236)
C: -95 - 0 (UniProt: Q12306)

PDB	External Database	Details
Met -136	-	initiating methionine
Ser -135	-	expression tag
Tyr -134	-	expression tag
Tyr -133	-	expression tag
His -132	-	expression tag
His -131	-	expression tag
His -130	-	expression tag
His -129	-	expression tag
His -128	-	expression tag
His -127	-	expression tag
Asp -126	-	expression tag
Tyr -125	-	expression tag
Asp -124	-	expression tag
Ile -123	-	expression tag
Pro -122	-	expression tag
Thr -121	-	expression tag
Thr -120	-	expression tag
Glu -119	-	expression tag
Asn -118	-	expression tag
Leu -117	-	expression tag
Tyr -116	-	expression tag
Phe -115	-	expression tag
Gln -114	-	expression tag
Gly -113	-	expression tag
Ile -112	-	expression tag
Thr -111	-	expression tag
Ser -110	-	expression tag
Leu -109	-	expression tag
Tyr -108	-	expression tag
Lys -107	-	expression tag
Lys -106	-	expression tag
Ala -105	-	expression tag
Gly -104	-	expression tag
Phe -103	-	expression tag
Leu -102	-	expression tag
Gln -101	-	expression tag
Leu -100	-	expression tag
Gly -99	-	expression tag
Ser -98	-	expression tag
Leu -97	-	expression tag
Gln -96	-	expression tag
Thr -34	Arg 64	engineered mutation
Glu -27	Arg 71	engineered mutation

C: 1 - 750 (UniProt: P10192)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	226245.4
All*	Total formula weight	226245.4

*Water molecules are not included.