9UPY
Cryo-EM structure of the ZQ16-bound GPR84 receptor-Gi complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | G-protein coupled receptor 84 | polymer | 395 | 43537.5 | 1 | UniProt (Q9NQS5) | Homo sapiens (human) | Inflammation-related G-protein coupled receptor EX33 |
| 2 | B (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 356 | 40691.3 | 1 | UniProt (P63096) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 359 | 39475.1 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | 2-hexylsulfanyl-4-oxidanyl-1~{H}-pyrimidin-6-one | non-polymer | 228.3 | 1 | Chemie (A1L9K) |
Sequence modifications
R: 4 - 390 (UniProt: Q9NQS5)
A: 1 - 354 (UniProt: P63096)
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Asp -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Asp 2 | - | expression tag |
| Lys 3 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | initiating methionine |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Gly 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131565.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 228.3 | |
| All* | Total formula weight | 131793.4 |






