9UOT

Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2G5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	nanobody Nb2G5	polymer	97	10899.0	1		Vicugna pacos
2	B (A)	Oxytocin receptor	polymer	489	54260.2	1	UniProt (P30559) Pfam (PF00001)	Homo sapiens (human)	OT-R

Sequence modifications

A: 1 - 223 (UniProt: P30559)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Ala 0	-	expression tag
His 65	Arg 65	conflict
Ala 153	Asp 153	conflict

A: 1001 - 1134 (PDB: 9UOT)
A: 272 - 389 (UniProt: P30559)

PDB	External Database	Details
Lys 325	Asn 325	conflict
Met 333	Thr 333	conflict
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65159.2
All*	Total formula weight	65159.2

*Water molecules are not included.