9UO8
Crystal structure of Keap1 in complex with a small molecule inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kelch-like ECH-associated protein 1 | polymer | 290 | 31652.3 | 2 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (house mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | C, I (A, B) | 4-ethoxy-~{N}-[4-[(4-ethoxyphenyl)sulfonylamino]-3-(2-oxidanylidene-2-pyrrol-1-yl-ethyl)naphthalen-1-yl]benzenesulfonamide | non-polymer | 633.7 | 2 | Chemie (A1L9D) | |||
| 3 | D, E, F, G, H... (A, B) | FORMIC ACID | non-polymer | 46.0 | 7 | Chemie (FMT) | |||
| 4 | L, M (A, B) | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A, B: 321 - 609 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Gly 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63304.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1589.6 | |
| All* | Total formula weight | 64894.3 |
