9UO5

Cryo-EM structure of the human IgG-Fc hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (E, F, G, H, I...)	Immunoglobulin gamma-1 heavy chain	polymer	251	28377.0	12	UniProt (P0DOX5)	Homo sapiens (human)	Immunoglobulin gamma-1 heavy chain NIE

Sequence modifications

E, F, G, H, I, J, B, K, L, A, D, C: 216 - 441 (UniProt: P0DOX5)

PDB	External Database	Details
Asp 208	-	expression tag
Tyr 209	-	expression tag
Lys 210	-	expression tag
Asp 211	-	expression tag
Asp 212	-	expression tag
Asp 213	-	expression tag
Asp 214	-	expression tag
Lys 215	-	expression tag
Asp 442	-	expression tag
Lys 443	-	expression tag
Ser 444	-	expression tag
Thr 445	-	expression tag
Gly 446	-	expression tag
Lys 447	-	expression tag
Pro 448	-	expression tag
Thr 449	-	expression tag
Leu 450	-	expression tag
Tyr 451	-	expression tag
Asn 452	-	expression tag
Val 453	-	expression tag
Ser 454	-	expression tag
Leu 455	-	expression tag
Val 456	-	expression tag
Met 457	-	expression tag
Ser 458	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	340524.1
All*	Total formula weight	340524.1

*Water molecules are not included.