9UJI
Crystal structure of the BTB domain mouse Keap1 in complex with CDDO-Im
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Kelch-like ECH-associated protein 1 | polymer | 130 | 14590.9 | 8 | UniProt (Q9Z2X8) Pfam (PF00651) | Mus musculus (house mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | I, K, L, N, O... (A, B, C, D, E...) | (13alpha,18alpha)-2-cyano-3-hydroxy-12-oxooleana-2,9(11)-dien-28-oic acid | non-polymer | 493.7 | 8 | Chemie (SXJ) | |||
| 3 | J, M (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
A, B, C, D, E, F, G, H: 50 - 179 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Ala 172 | Ser 172 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 116727.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4029.6 | |
| All* | Total formula weight | 120756.8 |
