9UJC
Crystal Structure of SME-1 E166A with cefpirome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase SME-1 | polymer | 275 | 30345.3 | 1 | UniProt (P52682) | Serratia marcescens | |
| 2 | B (A) | CEFOTAXIME, C3' cleaved, open, bound form | non-polymer | 397.4 | 1 | Chemie (CEF) | |||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 1 - 267 (UniProt: P52682)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ala 143 | Glu 170 | engineered mutation |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30345.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 599.6 | |
| All* | Total formula weight | 30944.9 |
