9UJ7
Crystal Structure of SME-1 E166A in complex with cefoperazone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Beta-lactamase SME-1 | polymer | 275 | 30345.3 | 2 | UniProt (P52682) | Serratia marcescens | |
| 2 | C, F (B, A) | Hydrolysed Cefoperazone | non-polymer | 533.6 | 2 | Chemie (DGK) | |||
| 3 | D (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 4 | E, G, H, I, J... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) PubChem (312) | |||
| 5 | L, M (B, A) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 267 (UniProt: P52682)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ala 143 | Glu 170 | engineered mutation |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60690.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1385.9 | |
| All* | Total formula weight | 62076.5 |
