9UJ5
Crystal structure of SME-1 E166A in complex with cefprozil
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase SME-1 | polymer | 275 | 30345.3 | 2 | UniProt (P52682) | Serratia marcescens | |
| 2 | C, H (A, B) | Acylated Cefprozil | non-polymer | 391.4 | 2 | Chemie (A1L87) | |||
| 3 | D, E, F, G, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) PubChem (312) | |||
| 4 | I (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 267 (UniProt: P52682)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ala 143 | Glu 170 | engineered mutation |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60690.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1022.2 | |
| All* | Total formula weight | 61712.7 |
