Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9UHI

FGFR1 kinase domain with a covalent inhibitor 9o

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Fibroblast growth factor receptor 1polymer31035264.52UniProt (P11362)
Pfam (PF07714)
Homo sapiens (human)FGFR-1,Basic fibroblast growth factor receptor 1,BFGFR,bFGF-R-1,Fms-like tyrosine kinase 2,FLT-2,N-sam,Proto-oncogene c-Fgr
2C, H
(A, B)
~{N}-[1-methyl-3-[3-[1-(2-morpholin-4-ylethyl)pyrazol-4-yl]quinoxalin-5-yl]indol-6-yl]propanamidenon-polymer509.62Chemie (A1EPF)
3D, E, F, G, I
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4J, K
(A, B)
waterwater18.0556Chemie (HOH)
Sequence modifications
A, B: 458 - 765 (UniProt: P11362)
PDBExternal DatabaseDetails
Gly 456-expression tag
Pro 457-expression tag
Ser 584Cys 584conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70529.0
Non-Polymers*Number of molecules7
Total formula weight1499.5
All*Total formula weight72028.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

PDB statisticsPDBj update infoContact PDBjnumon