9UGL

Cryo-EM structure of 5-HT2CR.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	5-hydroxytryptamine receptor 2C	polymer	401	45915.2	1	UniProt (P28335) Pfam (PF00001)	Homo sapiens (human)	5-HT-2C,5-HT2C,5-HTR2C,5-hydroxytryptamine receptor 1C,5-HT-1C,5-HT1C,Serotonin receptor 2C
2	B (A)	SB-242084	non-polymer		394.9	1	Chemie (A1L83) PubChem (3644637)

Sequence modifications

A: 40 - 393 (UniProt: P28335)

PDB	External Database	Details
Met 14	-	initiating methionine
Leu 15	-	expression tag
Thr 16	-	expression tag
Ile 17	-	expression tag
Ile 18	-	expression tag
Ala 19	-	expression tag
Leu 20	-	expression tag
Ser 21	-	expression tag
Tyr 22	-	expression tag
Ile 23	-	expression tag
Phe 24	-	expression tag
Cys 25	-	expression tag
Leu 26	-	expression tag
Val 27	-	expression tag
Phe 28	-	expression tag
Ala 29	-	expression tag
Asp 30	-	expression tag
Tyr 31	-	expression tag
Lys 32	-	expression tag
Asp 33	-	expression tag
Asp 34	-	expression tag
Asp 35	-	expression tag
Asp 36	-	expression tag
Gly 37	-	expression tag
Ala 38	-	expression tag
Pro 39	-	expression tag
Gly 394	-	expression tag
Arg 395	-	expression tag
Pro 396	-	expression tag
Leu 397	-	expression tag
Glu 398	-	expression tag
Val 399	-	expression tag
Leu 400	-	expression tag
Phe 401	-	expression tag
Gln 402	-	expression tag
Gly 403	-	expression tag
Pro 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45915.2
Non-Polymers*	Number of molecules	1
	Total formula weight	394.9
All*	Total formula weight	46310.0

*Water molecules are not included.