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Cryo-EM structure of HA21-bound alpha-synuclein fibril polymorph 6A6B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, D, E, F, B...)	Alpha-synuclein	polymer	140	14476.1	12	UniProt (P37840) Pfam (PF01387)	Homo sapiens (human)	Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
2	M, N, O, P, Q... (A, D, F, G, J...)	Gossypol	non-polymer		518.6	8	Chemie (GO3) PubChem (3503)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	173713.3
Non-Polymers*	Number of molecules	8
	Total formula weight	4148.4
All*	Total formula weight	177861.7

*Water molecules are not included.