9UEE
Crystal structure of (R)-carbonyl reductase mutant I51L/Y61F/D147E from Candida Parapsilosis in complex with NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | (R)-specific carbonyl reductase | polymer | 336 | 36017.2 | 4 | UniProt (A1X808) | Candida parapsilosis | 1-phenyl-1,2-ethanediol dehydrogenase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 336 (UniProt: A1X808)
| PDB | External Database | Details |
|---|---|---|
| Leu 51 | Ile 51 | engineered mutation |
| Phe 61 | Tyr 61 | engineered mutation |
| Glu 147 | Asp 147 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144069.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2915.3 | |
| All* | Total formula weight | 146984.3 |
